Uji Aktivitas Antibakteri Sediaan Sabun Cuci Tangan Ekstrak Bonggol Pisang Kepok Musa Paradisiaca L. terhadap Bakteri Staphylococcus aureus ATCC 25923 dan Escherichia coli ATCC 25922
Keywords:
ekstrak bonggol pisang kapok, escherichia coli, sabun cair cuci tangan, staphylococccus aureus
Abstract
Penelitian ini dilakukan untuk mengetahui aktivitas antibakteri sabun cuci tangan ekstrak bongkol pisang kepok terhadap bakteri Staphylococcus aureus ATCC 25923 dan Escherichia coli ATCC 2592. Sehingga, dapat digunakan sebagai alternatif bahan alam dan meminimalisasi penggunaan zat sintesis yang dapat menyebabbkan hipersensitifitas jika digunakan dalam jangka waktu yang lama. Formulasi sabun cair pada penelitian ini menggunakan variasi konsentrasi ekstrak bongkol pisang yaitu formula I (1%), formula II (2%), dan formula III (3%). Metoda pengujian aktivitas antibakteri dengan menggunakan metoda difusi dengan mengukur Konsentrasi Hambatan Minimum (KHM). Nilai KHM yang diperoleh dari pengujian terhadap bakteri Staphylococcus aureus ATCC 25923 adalah formula I 12.35 ± 0.83 mm, formula II 13.23 ± 0.35 mm dan formula III 15.23 ± 2.03 mm. Sedangkan, pada bakteri Escherichia coli ATCC 25922 formula I 12.04 ± 0.18 mm, formula II 12.71 ± 0.30 mm dan formula III 13.66 ± 0.88 mm.
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Cappuccino, J. G., dan Sherman, N. (2009). Manual Laboratorium Mikrobiologi. Jakarta: EGC Medical Publisher.
Chastelyna, A. J., & Wijayati, N. (2017). Uji Aktivitas Antibakteri Sabun Cair Ekstrak Daun Jati (Tectona Grandis L.f). Indonesian Journal of Chemical Science, 6(1), 72–76.
Farhan, H., Rammal, H., Hijazi, A., & Badran, B. (2012). Preliminary phytochemical screening and extraction of polyphenol from stems and leaves of a lebanese plant Malva parviflora L. International Journal of Current Pharmaceutical Research, 4(1), 55–59.
Fitri, I., Susilowati, D. T., & Rohmah, I. N. (2021). Uji Aktivitas Antibakteri Ekstrak Bonggol Pisang Kepok ( Musa paradisaca Linn . var . kepok ) TERHADAP Staphylococcus. Jurnal Ilmiah Pendidian IPA, 3(1), 24–30.
Handayani, D. S., Pranoto, Saputra, D. A., & Marliyana, S. D. (2019). Antibacterial activity of polyeugenol against staphylococcus aureus and escherichia coli. IOP Conference Series: Materials Science and Engineering, 578(1). https://doi.org/10.1088/1757-899X/578/1/012061
Jyothirmayi, N., Prasad, S. H. K. R., & Rao Mallikarjuna, N. (2012). Efficacy of ripened and unripened fruit extracts of musa x paradisiaca L. (bontha cultivar) against human pathogens. International Journal of Pharmacy and Pharmaceutical Sciences, 4(1), 455–460.
Kementrian Kesehatan. (2020). Pedoman COVID REV-4. Pedoman Pencegahan Dan Pengendalian Coronavirus Disease (COVID-19), 1(Revisi ke-4), 1–125.
Mahmood, A., Ngah, N., & Omar, M. N. (2011). Phytochemicals constituent and antioxidant activities in Musa x paradisiaca flower. European Journal of Scientific Research, 66(2), 311–318.
Mounika, A., Vijayanand, P., & Jyothi, V. (2017). Formulation and evaluation of poly herbal hand wash gel containing essential oils Standardization of Inoculums. International Journal of Pharmacy and Analytical Research, 6(4), 645–653.
Ningsih, A. putri, Nurmiati, & Aguestin, anthoni. (2013). Uji Aktivitas Antibakteri Ekstrak Kental Tanaman Pisang Kepok Kuning (Musa paradisiaca Linn.) terhadap Staphylococcus aureus dan Escherichia coli Antibacterial Activity of Crude Extracts of Pisang Kepok Kuning (Musa paradisiaca Linn.) Against Staphylococc. Jurnal Biologi Universitas Andalas (J. Bio. UA.), 2(3), 207–213.
Rahman, M. M., & Richardson, A. (2010). Antibacterial activity of propolis and honey against Staphylococcus aureus and Escherichia coli. African Journal of Microbiology Research, 4(18), 1872–1878.
Rahmawati, N., Widiyastuti, Y., Purwanto, R., Lestari, S. S., Sene, I. H. A., & Bakari, Y. (2020). Medicinal Plants Used by Traditional Healers for the Treatment of Various Diseases in Ondae Sub-ethnic of Poso District in Indonesia. 22(Ishr 2019), 460–468. https://doi.org/10.2991/ahsr.k.200215.089
Rakotoarivelo, N. H., Rakotoarivony, F., Ramarosandratana, A. V., Jeannoda, V. H., Kuhlman, A. R., Randrianasolo, A., & Bussmann, R. W. (2015). Medicinal plants used to treat the most frequent diseases encountered in Ambalabe rural community, Eastern Madagascar. Journal of Ethnobiology and Ethnomedicine, 11(1). https://doi.org/10.1186/s13002-015-0050-2
Refdanita, Maksum, R., Nurgani, A., & Endang, P. (2004). Pola Kepekaan Kuman Terhadap Antibiotika Di Ruang Rawat Intensif Rumah Sakit Fatmawati Jakarta Tahun 2001 – 2002. Makara Kesehatan, 8(2), 41–48.
Utami, S. M., & Denanti, I. R. (2020). Uji Efektivitas Antibakteri Sediaan Sabun Cair Cuci Tangan Dari Lendir Lidah Buaya (Aloe barbadensis Miller) Terhadap Eschericia coli dan Staphylococcus aureus. Edu Masda Journal, 2(2), 63. https://doi.org/10.52118/edumasda.v2i2.14
Uthayasooriyan, M., Pathmanathan, S., Ravimannan, N., & Sathyaruban, S. (2016). Formulation of alternative culture media for bacterial and fungal growth. Der Pharmacia Lettre, 8(1), 444–449.
Zarrindokht Emami-Karvani. (2012). Antibacterial activity of ZnO nanoparticle on Gram-positive and Gram-negative bacteria. African Journal of Microbiology Research, 5(18), 1368–1373. https://doi.org/10.5897/ajmr10.159
Published
2021-11-28
How to Cite
Nurleni, N., Firdiawan, A., Wahyuni, Y., & Lestari, D. (2021). Uji Aktivitas Antibakteri Sediaan Sabun Cuci Tangan Ekstrak Bonggol Pisang Kepok Musa Paradisiaca L. terhadap Bakteri Staphylococcus aureus ATCC 25923 dan Escherichia coli ATCC 25922. Jurnal Farmasetis, 10(2), 167-174. https://doi.org/https://doi.org/10.32583/farmasetis.v10i2.1911
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Articles
