Metaanalisis Hubungan Covid-19 dengan Persalinan Prematur
Keywords:
covid-19, persalinan prematur, kehamilan, metaanalisis
Abstract
Wanita hamil yang terinfeksi COVID-19 memiliki risiko lebih tinggi untuk melahirkan secara prematur. Penelitian ini belum banyak dilakukan di Indonesia sehingga peneliti tertarik untuk mengadakan penelitian tentang risiko persalinan prematur pada ibu hamil terinfeksi COVID-19. Tujuan penelitian untuk mengetahui hubungan COVID-19 tentang persalinan prematur. Metaanalisis dilakukan untuk mengulas artikel-artikel yang ditemukan dari beberapa database yaitu Google Scholar, PubMed, dan ScienceDirect. Artikel yang digunakan adalah artikel yang dipublikasi dari tahun 2020-2021. Kata kunci yang digunakan untuk mencari artikel yang sesuai adalah COVID-19 DAN kehamilan DAN "kelahiran prematur". Kriteria inklusi yang digunakan adalah full paper, bahasa Inggris atau Indonesia, desain studi observasional, dan mencantumkan hasil Odds Ratio (aOR). Hasil pencarian artikel dicantumkan dalam diagram PRISMA dan dianalisis menggunakan aplikasi Review Manager 5.3. Sebanyak 6 artikel menunjukkan kelompok percobaan heterogen (I2= 88%; p< 0,001), oleh karena itu penelitian ini menggunakan model efek acak. Hasil studi menunjukkan ibu hamil yang terinfeksi COVID-19 dapat meningkatkan risiko 1,33 kali dibandingkan persalinan yang tak terinfeksi COVID-19 (aOR= 1,33; CI 95%= 0,75 hingga 2,33; p= 0,330). Ibu hamil yang terinfeksi COVID-19 memiliki risiko lebih 1,33 kali lebih tinggi untuk melahirkan prematur.
References
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Zhang, L, Jiang, Y, Wei, M, Cheng, B, Zhou, X, Li, J, Hu, R. (2020). Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province. Zhonghua Fu Chan Ke Za Zhi, 55((3)), 166–171. https://doi.org/doi: 10.3760/¬cma.j.cn112141-20200218-00111.
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Adhikari, E. H., Moreno, W., Zofkie, A. C., MacDonald, L., McIntire, D. D., Collins, R., & Spong, C. Y. (2020). Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection. JAMA network open, 3(11), e2029256. https://doi.org/10.1001/jamanetworkopen.2020.29256.
Allotey J, Stallings E, Bonet M, Yap M, Chatterjee S, Kew T, Debenham L, et al; for PregCOV-19 Living Systematic Review Consortium. Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis. BMJ. 2020 Sep 1;370:m3320. doi: 10.1136/bmj.m3320. PMID: 32873575; PMCID: PMC7459193.
Altimier L & Phillips R (2016). The neonatal integrative developmental care model: advanced clinical applications of the seven core measures for neuroprotective family-centered developmental care. N.born Infant Nurs, 16(4): 230–244. https://doi.org/10.1053/j.nainr.2016.09.030.
Arnaez, J, Ochoa-Sangrador, C, Caserío, S, Gutiérrez, EP, Jiménez, MP, Castañón, L, Garcia-Alix, A. (2021). Lack of changes in preterm delivery and stillbirths during COVID-19 lockdown in a European region. European Journal of Pediatrics. https://doi.org/10.1007/s00431-021-03984-6.
Atmojo, j. (2020). Infeksi Covid-19 pada Kehamilan dan Persalinan : A review. Jurnal Informasi Kesehatan Indonesia (JIKI), 6(1), 1-5. doi:10.31290/jiki.v6i1.1503
Bellos, I, Pandita, A, and Panza, R. (2021). Maternal and perinatal outcomes in pregnant women infected by SARS-CoV-2: A meta-analysis. European Journal of Obstetrics and Gynecology and Reproductive Biology, 256, 194–204. https://doi.org/10.1016/-j.ejogrb.2020.11.038.
Chen, S, Huang, B, Luo, D, Li, X, Yang, F, Zhao, Y, Huang, B. (2020). Pregnancy with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases. Zhonghua Bing Li Xue Za Zhi, 49((5)), 418–423. https://doi.org/10.3760/cma.j.cn112151-20200225-00138.
Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W, Li J et al., (2020). Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 395(10226): 809–815. https://doi.org/10.1016/S0140-6736¬(20)30360-3.
Dana, PM, Kolahdooz, F, Sadoughi, F, Moazzami, B, Chaichian, S, and Asemi, Z. (2020). COVID-19 and pregnancy: A Review of current knowledge. Infezioni in Medicina, 28, 46–51.
Di Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M, Vecchiet J, Nappi L, Scambia G, Berghella V, D'Antonio F. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2020 May;2(2):100107. doi: 10.1016/j.ajogmf.2020.100107.
Du, M, Yang, J, Han, N, Liu, M, and Liu, J. (2021). Association between the COVID-19 pandemic and the risk for adverse pregnancy outcomes: a cohort study. BMJ Open, 11(2), e047900. https://doi.org/10.1136/¬bmjopen-2020-047900.
Fowler C, Green J, Elliott D, Petty J & Whiting L (2019). The forgotten mothers of extremely preterm babies: A qualitative study. Journal of Clinical Nursing, 28(11-12): 2124–2134. https://doi.org/10.1111/jocn.14820.
Handayani, R. T., Widiyanto, A., Atmojo, J. T., & Setyorini, C. (2020). Effect of Antenatal Mental Health Disorder on Fetal Growth: A Systematic Review. Journal of Maternal and Child Health, 5(2), 147-153. https://doi.org/10.26911/thejmch.2020.05.02.04.
Liu, D, Li, L, Zheng, D, Wang, J, Yang, L, Zheng, C, Wu, X. (2020). Pregnancy and Perinatal Outcomes. American Journal of Roentgenology, (July), 1–6.
Meyer, R, Bart, Y, Tsur, A, and Yinon, Y. (2020). A marked decrease in preterm deliveries during the coronavirus disease 2019 pandemic. American Journal of Obstetrics & Gynecology, 7(May), 19–21.
Pérez, OM, Rodriguez, PP, Hernandez, MM, Pardilla, MBE, Perez Perez, N, Hernandez, MRV, Sainz Bueno, JA. (2020). The association between COVID-19 and preterm delivery: A cohort study with a multivariate analysis. BMJ Open. https://-doi.org/10.1101/2020.09.05.20188458.
Pirjani, R, Hosseini, R, Soori, T, Rabiei, M, Hosseini, L, Abiri, A, Sepidarkish, M. (2020). Maternal and neonatal outcomes in COVID-19 infected pregnancies: a prospective cohort study. Journal of Travel Medicine, 27(7), 1–7. https://¬doi.org/10.1093/jtm/taaa158.
Pulinx, B, Kieffer, D, Michiels, I, Petermans, S, Strybol, D, Delvaux, S, Maurissen, W. (2020). Vertical transmission of SARS-CoV-2 infection and preterm birth. European Journal of Clinical Microbiology and Infectious Diseases, 39(12), 2441–2445. https://doi.org/10.1007/s10096-020-03964-y.
Qiao J (2020). What are the risks of COVID-19 infection in pregnant women? Lancet (London, England), 395(10226): 760–762. https://doi.org/¬10.¬1016/¬S0140-6736(20)30365-2.
Sentilhes L, De Marcillac F, Jouffrieau C, et al. Coronavirus disease 2019 in pregnancy was associated with maternal morbidity and preterm birth. Am J Obstet Gynecol 2020;223:914.e1-15. doi: 10.1016/j.ajog.2020.06.022.
Schwartz DA & Graham AL (2020). Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections. Viruses, 12(2): 194. https://doi.org/10.3390/v12020194.
Yang, R, Mei, H, Zheng, T, Fu, Q, Zhang, Y, Buka, S, Zhou, A. (2020). Pregnant women with COVID-19 and risk of adverse birth outcomes and maternal-fetal vertical trans¬mission: a population-based cohort study in Wuhan, China. BMC Medicine, 18(1), 1–7. https://doi.-org/¬¬10.1186/s12916-020-01798-1.
Zeng, Y, Lin, L, Yan, Q, Wei, W, Xiang Yang, B, Huang, R, Chen, D. (2020). Update on clinical outcomes of women with COVID-19 during pregnancy. International Journal of Gynecology and Obstetrics, 150(2), 264–266. https://doi.org/10.1002/ijgo.13236.
Zhang, L, Jiang, Y, Wei, M, Cheng, B, Zhou, X, Li, J, Hu, R. (2020). Analysis of the pregnancy outcomes in pregnant women with COVID-19 in Hubei Province. Zhonghua Fu Chan Ke Za Zhi, 55((3)), 166–171. https://doi.org/doi: 10.3760/¬cma.j.cn112141-20200218-00111.
Zhu, H, Wang, L, Fang, C, Peng, S, Zhang, L, Chang, G, Zhou, W. (2020). Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Translational Pediatrics, 9(1), 51–60. https://¬doi.org/10.21037/tp.2020.02.06.
Published
2021-11-02
How to Cite
Widiyanto, A., Atmojo, J., PH, L., Fajriah, A., Putri, S., Nahak, M., & Anulus, A. (2021). Metaanalisis Hubungan Covid-19 dengan Persalinan Prematur. Jurnal Keperawatan, 13(3), 791-798. https://doi.org/https://doi.org/10.32583/keperawatan.v13i3.1772
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Articles
