Madu sebagai Agen Oral Care pada Pasien Terventilasi Mekanik di ICU: Narrative Review
Keywords:
ICU, madu, oral care, VAP, ventilasi mekanik
Abstract
Pasien kritis dengan penggunaan ventilasi mekanik di ICU rentan mengalami gangguan pada kesehatan mulut sehingga beresiko mengembangkan kejadian Ventilator Associated Pneumonia (VAP). Oral care menggunakan madu berpotensi efektif dalam menghambat kolonisasi mikroba patogen di mulut, namun penelitian yang membahas oral care madu di area critical care masih terbatas. Artikel ini bertujuan untuk menilai efektivitas oral care madu pada pasien terventilasi mekanik di ICU. Kami melakukan narrative review terhadap artikel yang dipublikasikan pada tahun 2011-2021 dengan menggunakan empat (4) database yaitu Medline (Pubmed), CINAHL (Ebsco), Science Direct dan Google Scholar untuk artikel yang berfokus pada penggunaan madu sebagai agen oral care pada pasien terventilasi mekanik. Tiga independent reviewers menganalisa berdasarkan kriteria inklusi dan eksklusi yang telah ditetapkan. Melalui pencarian data dasar diperoleh 2.514 artikel. Berdasarkan PRISMA flowchart dan setelah tinjauan manual hanya 7 penelitian yang sesuai dan diidentifikasi. Hasil telaah menunjukkan bahwa madu yang digunakan 2 kali sehari sebagai agen oral care dengan cara berkumur maupun teknik oles terbukti efektif untuk menghambat kolonisasi bakteri penyebab infeksi mulut; mengatasi berbagai masalah mulut pasien terventilasi mekanik seperti xerostomia, mukositis dan gangguan keasaman pH, serta berpotensi mencegah kejadian VAP.
References
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Alzahrani, H. A., Alsabehi, R., Boukraa, L., Abdellah, F., Bellik, Y., & Bakhotmah, B. A. (2012). Antibacterial and antioxidant potency of floral honeys from different botanical and geographical origins. Molecules, 17(9), 10540-10549. doi:10.3390/molecules170910540
Amiri, H., Ramezani-Badr., Farhad, S., Naseh., & Nasseri, K. (2020). Comparative efficacy of honey 12.5% and chlorhexidine 0.2% mouthwashes on the oropharyngeal bacterial colonization in mechanically-ventilated patients: a randomized controlled trial. Jounal of Traditional Chinese Medicine., 4(3), 440-446.
Andrea, B. (2011). Systemic manifestations of oral diseases. Journal of Oral and Maxillofacial Pathology, 15(2), 44-157.
Anggraeni, D. T., Hayati, A. T., & Nur'aeni, A. (2018). The effect of oral care with additional topical agents of honey on the oral health status of patients with endotracheal tubes attached in the ICU.
Arigbede, A., & Babatope., B. (2012). Periodontitis and systemic diseases : a Narrative Review. Journal of Indian Society of Periodontology, 16(4), 487-491. doi:DOI : 10.4103/0972-124X.106878
Bahramnezhad, F., Dehghan Nayeri, N., Bassampour, S. S., Khajeh, M., & Asgari, P. (2015). Honey and Radiation-Induced Stomatitis in Patients With Head and Neck Cancer. Iran Red Crescent Med J, 17(10), e19256. doi:10.5812/ircmj.19256
Ban, K. O. (2011). The effectiveness of an evidence-based nursing care program to reduce ventilator-associated pneumonia in a Korean ICU. Intensive Crit Care Nurs, 27(4), 226-232. doi:10.1016/j.iccn.2011.04.001
Bogdanov, S., Jurendic, T., Sieber, R., & Gallmann, P. (2008). Honey for nutrition and health: a review. J Am Coll Nutr, 27(6), 677-689. doi:10.1080/07315724.2008.10719745
Chastre, J., & Fagon, J.-Y. (2002). Ventilator-associated Pneumonia. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 165, 867-903. doi:10.1164/rccm.2105078
Das, S., Mohanty, S., & Debnath, S. (2020). Effect Of Honey Mouth-Care On Xerostomia Among Semiconscious And Unconscious Patients. International Journal Of Research In Pharmaceutical Sciences, 11(1), 1018-1024. doi:Https://Doi.Org/10.26452/Ijrps.V11i1.1930.
Evans, J., & Flavin, S. (2008). Honey: a guide for healthcare professionals. British Journal of Nursing, 17(15), 24-30. doi:10.12968/bjon.2008.17.Sup6.30707
Heo, S. M., Haase, E. M., Lesse, A. J., Gill, S. R., & Scannapieco, F. A. (2008). Genetic relationships between respiratory pathogens isolated from dental plaque and bronchoalveolar lavage fluid from patients in the intensive care unit undergoing mechanical ventilation. G Clinical Infectious Diseases, 47(12), 1562-1570.
Jain, A., Bhaskar, D. J., Gupta, D., , , Agali, C., Gupta, V., Gupta, R. K., . . . Chaturvedi, M. (2015). Comparative evaluation of honey, chlorhexidine gluconate (0.2%) and combination of xylitol and chlorhexidine mouthwash (0.2%) on the clinical level of dental plaque: A 30 days randomized control trial. Perspectives in Clinical Research, 6(53-58). doi:doi:10.4103/2229-3485.148819
James P, Worthington HV, & C, P. (2017). Chlorhexidine mouthrinse as an adjunctive treatment for gingival health (Review). Cochrane Database Syst Rev, 3.
Kalanuria, A. A., Zai, W., & Mirski, M. (2014). Ventilator-associated pneumonia in the ICU. Critical Care, 18(208). doi:10.1186/cc137
Koeman M, van der Ven AJ, & Hak E. (2006). Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med, 173(12), 1348-1355.
Konuk-Sener, D., Aydin, M., Cangur, S., & Guven, E. (2019). The Effect of Oral Care with Chlorhexidine, Vitamin E and Honey on Mucositis in Pediatric Intensive Care Patients: A Randomized Controlled Trial. J Pediatr Nurs, 45, e95-e101. doi:10.1016/j.pedn.2019.02.001
Labeau SO, Van de Vyver K, Brusselaers N, Vogelaers D, & SI, B. (2011). Prevention of ventilator-associated pneumonia with oral antiseptiks: a systematic review and Meta-analysis. Lancet Infect Dis, 11(11), 845-854.
Maharani, l. s. (2018). Pengaruh oral hygiene menggunakan madu terhadap tingkat keasaman saliva pada pasien yang di rawat di ruang ICU.
Mariyam, & Alfiyanti, D. (2014). Penggunaan Madu Dalam Oral Hygiene Sebagai Inhibitor Koloni Bakteri Pada Anak Yang Dirawat Di PICU. Jurnal Keperawatan Anak, 2(2), 78-83.
Othman, A. A., & Abdelazim, M. S. (2017). Ventilator-associated pneumonia in adult intensive care unit prevalence and complications. The Egyptian Journal of Critical Care Medicine, 5(2), 61-63. doi:10.1016/j.ejccm.2017.06.001
Scholte, J. B., van Dessel, H. A., Linssen, C. F., Bergmans, D. C., Savelkoul, P. H., Roekaerts, P. M., & van Mook, W. N. (2014). Endotracheal aspirate and bronchoalveolar lavage fluid analysis: interchangeable diagnostic modalities in suspected ventilator-associated pneumonia? J Clin Microbiol, 52(10), 3597-3604. doi:10.1128/JCM.01494-14
Tartaglia, G. M., Tadakamadla, S. K., Connelly, S. T., Sforza, C., & Martin, C. (2019). Adverse events associated with home use of mouthrinses: a systematic review. Ther Adv Drug Saf, 10, 2042098619854881. doi:10.1177/2042098619854881
Ahmadi - Motamayel, F., Hendi, S. S., Alikhani, M. Y., & Khamverdi, Z. (2012). Antibacterial Activity of Honey on Cariogenic Bacteria. Journal of Dentistry, Tehran University of Medical Sciences, 10(1), 10-15.
Al Jaouni, S. K., Al Muhayawi, M. S., Hussein, A., Elfiki, I., Al-Raddadi, R., Al Muhayawi, S. M., . . . Harakeh, S. (2017). Effects of Honey on Oral Mucositis among Pediatric Cancer Patients Undergoing Chemo/Radiotherapy Treatment at King Abdulaziz University Hospital in Jeddah, Kingdom of Saudi Arabia. Evid Based Complement Alternat Med, 2017, 5861024. doi:10.1155/2017/5861024
Alzahrani, H. A., Alsabehi, R., Boukraa, L., Abdellah, F., Bellik, Y., & Bakhotmah, B. A. (2012). Antibacterial and antioxidant potency of floral honeys from different botanical and geographical origins. Molecules, 17(9), 10540-10549. doi:10.3390/molecules170910540
Amiri, H., Ramezani-Badr., Farhad, S., Naseh., & Nasseri, K. (2020). Comparative efficacy of honey 12.5% and chlorhexidine 0.2% mouthwashes on the oropharyngeal bacterial colonization in mechanically-ventilated patients: a randomized controlled trial. Jounal of Traditional Chinese Medicine., 4(3), 440-446.
Andrea, B. (2011). Systemic manifestations of oral diseases. Journal of Oral and Maxillofacial Pathology, 15(2), 44-157.
Anggraeni, D. T., Hayati, A. T., & Nur'aeni, A. (2018). The effect of oral care with additional topical agents of honey on the oral health status of patients with endotracheal tubes attached in the ICU.
Arigbede, A., & Babatope., B. (2012). Periodontitis and systemic diseases : a Narrative Review. Journal of Indian Society of Periodontology, 16(4), 487-491. doi:DOI : 10.4103/0972-124X.106878
Bahramnezhad, F., Dehghan Nayeri, N., Bassampour, S. S., Khajeh, M., & Asgari, P. (2015). Honey and Radiation-Induced Stomatitis in Patients With Head and Neck Cancer. Iran Red Crescent Med J, 17(10), e19256. doi:10.5812/ircmj.19256
Ban, K. O. (2011). The effectiveness of an evidence-based nursing care program to reduce ventilator-associated pneumonia in a Korean ICU. Intensive Crit Care Nurs, 27(4), 226-232. doi:10.1016/j.iccn.2011.04.001
Bogdanov, S., Jurendic, T., Sieber, R., & Gallmann, P. (2008). Honey for nutrition and health: a review. J Am Coll Nutr, 27(6), 677-689. doi:10.1080/07315724.2008.10719745
Chastre, J., & Fagon, J.-Y. (2002). Ventilator-associated Pneumonia. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 165, 867-903. doi:10.1164/rccm.2105078
Das, S., Mohanty, S., & Debnath, S. (2020). Effect Of Honey Mouth-Care On Xerostomia Among Semiconscious And Unconscious Patients. International Journal Of Research In Pharmaceutical Sciences, 11(1), 1018-1024. doi:Https://Doi.Org/10.26452/Ijrps.V11i1.1930.
Evans, J., & Flavin, S. (2008). Honey: a guide for healthcare professionals. British Journal of Nursing, 17(15), 24-30. doi:10.12968/bjon.2008.17.Sup6.30707
Heo, S. M., Haase, E. M., Lesse, A. J., Gill, S. R., & Scannapieco, F. A. (2008). Genetic relationships between respiratory pathogens isolated from dental plaque and bronchoalveolar lavage fluid from patients in the intensive care unit undergoing mechanical ventilation. G Clinical Infectious Diseases, 47(12), 1562-1570.
Jain, A., Bhaskar, D. J., Gupta, D., , , Agali, C., Gupta, V., Gupta, R. K., . . . Chaturvedi, M. (2015). Comparative evaluation of honey, chlorhexidine gluconate (0.2%) and combination of xylitol and chlorhexidine mouthwash (0.2%) on the clinical level of dental plaque: A 30 days randomized control trial. Perspectives in Clinical Research, 6(53-58). doi:doi:10.4103/2229-3485.148819
James P, Worthington HV, & C, P. (2017). Chlorhexidine mouthrinse as an adjunctive treatment for gingival health (Review). Cochrane Database Syst Rev, 3.
Kalanuria, A. A., Zai, W., & Mirski, M. (2014). Ventilator-associated pneumonia in the ICU. Critical Care, 18(208). doi:10.1186/cc137
Koeman M, van der Ven AJ, & Hak E. (2006). Oral decontamination with chlorhexidine reduces the incidence of ventilator-associated pneumonia. Am J Respir Crit Care Med, 173(12), 1348-1355.
Konuk-Sener, D., Aydin, M., Cangur, S., & Guven, E. (2019). The Effect of Oral Care with Chlorhexidine, Vitamin E and Honey on Mucositis in Pediatric Intensive Care Patients: A Randomized Controlled Trial. J Pediatr Nurs, 45, e95-e101. doi:10.1016/j.pedn.2019.02.001
Labeau SO, Van de Vyver K, Brusselaers N, Vogelaers D, & SI, B. (2011). Prevention of ventilator-associated pneumonia with oral antiseptiks: a systematic review and Meta-analysis. Lancet Infect Dis, 11(11), 845-854.
Maharani, l. s. (2018). Pengaruh oral hygiene menggunakan madu terhadap tingkat keasaman saliva pada pasien yang di rawat di ruang ICU.
Mariyam, & Alfiyanti, D. (2014). Penggunaan Madu Dalam Oral Hygiene Sebagai Inhibitor Koloni Bakteri Pada Anak Yang Dirawat Di PICU. Jurnal Keperawatan Anak, 2(2), 78-83.
Othman, A. A., & Abdelazim, M. S. (2017). Ventilator-associated pneumonia in adult intensive care unit prevalence and complications. The Egyptian Journal of Critical Care Medicine, 5(2), 61-63. doi:10.1016/j.ejccm.2017.06.001
Scholte, J. B., van Dessel, H. A., Linssen, C. F., Bergmans, D. C., Savelkoul, P. H., Roekaerts, P. M., & van Mook, W. N. (2014). Endotracheal aspirate and bronchoalveolar lavage fluid analysis: interchangeable diagnostic modalities in suspected ventilator-associated pneumonia? J Clin Microbiol, 52(10), 3597-3604. doi:10.1128/JCM.01494-14
Tartaglia, G. M., Tadakamadla, S. K., Connelly, S. T., Sforza, C., & Martin, C. (2019). Adverse events associated with home use of mouthrinses: a systematic review. Ther Adv Drug Saf, 10, 2042098619854881. doi:10.1177/2042098619854881
Published
2021-12-01
How to Cite
Atrie, U., Kosasih, C., & Nuraeni, A. (2021). Madu sebagai Agen Oral Care pada Pasien Terventilasi Mekanik di ICU: Narrative Review. Jurnal Keperawatan, 13(4), 735-750. https://doi.org/https://doi.org/10.32583/keperawatan.v13i4.1550
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Articles
