Meta Analisis Risk Ratio dan Hazard Ratio Kematian ODHA yang Terinfeksi Covid-19
Keywords:
covid-19, hazard ratio, hiv/aids, meta analisis, risk ratio
Abstract
Patogenisitas COVID-19 bisa dipercepat pada orang yang hidup dengan HIV. Bukti terbaru telah menunjukkan substansial hubungan antara infeksi saluran pernapasan bawah terkait Coronavirus (Lower Respiratory Tract Infections (LRTI) dan peningkatan risiko kematian pada individu dengan gangguan kekebalan termasuk orang dengan HIV/AIDS. Meta analisis ini dibuat untuk mengestimasi risiko kematian orang dengan HIV/AIDS (ODHA) yang terinfeksi COVID-19 berdasarkan bukti yang dilaporkan dari berbagai belahan dunia. Pelaporan meta analisis ini dilakukan berdasarkan PRISMA. Pencarian basis data dilakukan Januari - Mei 2021, sepuluh dari 2062 artikel masuk ke dalam analisis RevMan menggunakan risk ratio dan hazard ratio. Hasil risk ratio (RR) pasien COVID-19 yang menderita HIV untuk meninggal dunia adalah 4.32 [95% CI (1.24, 15.05)]; p-value 0.002, sedangkan hazard ratio (HR) 10.36 [95% CI (7.11, 15.11)]; p-value <0,001. ODHA yang terinfeksi COVID-19 memiliki risiko untuk mengalami kematian berkisar antara 4 hingga 10 kali dibandingkan pasien COVID-19 tanpa HIV/AIDS. Kematian sebagian besar disebabkan oleh perburukan COVID-19 dengan koinfeksi HIV/AIDS seperti tuberculosis, hipertensi, diabetes, dan chronic obstructive pulmonary disease.
References
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Liu Y, Bi L, Chen Y, Wang Y, Fleming J, Yu Y, et al. (2020). Active or latent tuberculosis increases susceptibility to COVID-19 and disease severity. medRxiv., 1;2020.03.10.20033795.
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Ogimi C, Waghmare AA, Kuypers JM, Xie H, Yeung CC, Leisenring WM, et al. (2017). Clinical significance of human coronavirus in Bronchoalveolar lavage samples from hematopoietic cell transplant recipients and patients with hematologic malignancies. Clin Infect Dis., ;64(11):1532–9.
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Sarkar, S., Khanna, P., & Singh, A. K. . (2021). (2021). Impact of COVID‐19 in patients with concurrent co‐infections: a systematic review and meta‐analyses. . Journal of Medical Virology,, 93(4), 2385-2395.
Sigel K, Swartz T, Golden E, et al. (2020). Covid-19 and People with HIV Infection: Outcomes for Hospitalized Patients in New York City. Clin Infect Dis., ciaa880. doi:10.1093/cid/ciaa880.
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Wallinga J, T. P. (2004). Different epidemic curves for severe acute respiratory syndrome reveal similar impacts of control measures. . Am J Epidemiol. , 160(6):509–16.
Atmojo, J. T., Maylanda, V. E., Prastiwi, A. T., Darmayanti, A. T., & Kuntari, S. (2019). Faktor-Faktor yang Memengaruhi Ketahanan Hidup Pasien HIV/AIDS: A review. Jurnal Informasi Kesehatan Indonesia, 5(2), 159-164. https:/ / doi. org /10.31290 / jiki.v5i2.1492.
Bhaskaran, K., Rentsch, C. T., MacKenna, B., Schultze, A., Mehrkar, A., Bates, C. J.,Goldacre, B. et al. (2021). HIV infection and COVID-19 death: a population-based cohort analysis of UK primary care data and linked national death registrations within the OpenSAFELY platform. The Lancet HIV,, 8(1), e24-e32. https://doi.org/10.1016/S2352-3018(20)30305-2.
Boulle, A., Davies, M. A., Hussey, H., Ismail, M., Morden, E., Vundle, Z.,& Stek, C. (2020). Risk factors for COVID-19 death in a population cohort study from the Western Cape Province, South Africa. Clinical infectious diseases: an official official publication of the Infectious Diseases Society of America. doi: 10.1093/cid/ciaa1198.
Cui J, Li F, Shi ZL. (2019). Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol., 17(3):181–92.
Del Amo, J., Polo, R., Moreno, S., Díaz, A., Martínez, E., Arribas, J. R., Hernán, M. A et al. (2020). Incidence and severity of COVID-19 in HIV-positive persons receiving antiretroviral therapy: a cohort study. Annals of internal medicine,, 173(7), 536-541. doi:10.7326/M2 0-3689.
Gao, Y., Liu, M., Chen, Y., Shi, S., Geng, J. and Tian, J. (2020). Association between tuberculosis and COVID-19 severity and mortality: A rapid systematic review and meta-analysis. J Med Virol., doi:10.1002/jmv.26311.
Geretti, A. M., Stockdale, A. J., Kelly, S. H., Cevik, M., Collins, S., Waters, L., Semple, M. et al. (2020). Outcomes of COVID-19 related hospitalisation among people with HIV in the ISARIC WHO Clinical Characterisation Protocol UK Protocol: prospective observational study. 10.1093/cid/ciaa1605.
Griffith GJ, Morris TT, Matt Tudball M, Herbert A, Mancano G, Pike L, et al. . (2020. ). Collider bias undermines our understanding of COVID-19 disease risk and severity. . doi: 10.1038/s41467-020-19478-2.
Hadi, Y. B., Naqvi, S. F., Kupec, J. T., & Sarwari, A. R. (2020). (2020). Characteristics and outcomes of COVID-19 in patients with HIV: a multicentre research network study. Aids,, 34(13), F3-F8. doi: 10.1097/QAD.0000000000002666.
Handayani, R. T., Arradini, D., Darmayanti, A. T., Widiyanto, A., & Atmojo, J. T. (2020). Pandemic Covid-19, Body Immunity Response, and Herd Immunity. Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal, 10(3), 373-380.
Huang, J., Xie, N., Hu, X., Yan, H., Ding, J., Liu, P., & Wang, X. (2020). Epidemiological, virological and serological features of COVID-19 cases in people living with HIV in Wuhan City: A population-based cohort study. Clinical infectious diseases:an official publication of the Infectious Diseases Society of America., DOI:10.1093/cid/ciaa1186.
Jacques L. Tamuzi. (2020). Implications of COVID-19 in high burden countries for HIV/TB: A systematic review of evidence. BMC Infectious Diseases, 2-18.
Kalyanaraman Marcello R, Dolle J, Grami S, et al. (2020). Characteristics and Outcomes of COVID-19 Patients in New York City's Public Hospital System. Preprint. medRxiv., 05.29.20086645.doi:10.1101/2020.05.29.20086645.
Karmen-Tuohy, S., Carlucci, P. M., Zervou, F. N., Zacharioudakis, I. M., Rebick, G., Klein, E.,Rahimian, J. et al. (2020). Outcomes among HIV-positive patients hospitalized with COVID-19. Journal of acquired immune deficiency syndromes (1999)., 10.1097/QAI.0000000000002423.
Lee MJ, Smith C, Snell LB, Lwanga J, Simons R, Fitzgerald N, et al. (2020). Comparative outcomes in hospital admissions with COVID-19 in people living with HIV and people living without HIV: A retrospective study. In: 23rd International AIDS Conference, abstract LLBPEB09. San Fransisco.
Li G, F. Y. (2020;). Coronavirus infections and immune responses. . J Med Virol. , 92(4):424–32.
Li G, Fan Y, Lai Y, Han T, Li Z, Zhou P, et al. (2020). Li G, Fan Y, Lai Y, Han T, Coronavirus infections and immune responses. J Med Virol, 92(4):424–32.
Liberati, A. Altman, Tetzlaff, Mulrow, Gotzsche, Ioannidis, Clarke, Devereaux, Kleijnen, and Moher. (2009). (2009) ‘The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration. ’, Bmj, 339(jul21 1), , pp. b2700–b2700. doi: 10.1136/bmj.b2700.
Lin Q, C. A. (2018). Modeling the spread of Middle East respiratory syndrome coronavirus in Saudi Arabia. Stat Methods Med Res. , 27(7):1968–78.
Lipsitch M, Cohen T, Cooper B, Robins JM, Ma S, James L, et al. (2003). Transmission dynamics and control of severe acute respiratory syndrome. Science (New York, NY)., 300(5627):1966–70.
Liu Y, Bi L, Chen Y, Wang Y, Fleming J, Yu Y, et al. (2020). Active or latent tuberculosis increases susceptibility to COVID-19 and disease severity. medRxiv., 1;2020.03.10.20033795.
Motta I, Centis R, D'Ambrosio L, et al. (2020). Tuberculosis, COVID-19 and migrants: Preliminary analysis of deaths occurring in 69 patients from two cohorts. Pulmonology, 26(4):233-240. doi:10.1016/ j.pulmoe. 2020.05.002.
Ogimi C, Englund JA, Bradford MC, Qin X, Boeckh M, Waghmare A. (2019). Characteristics and outcomes of coronavirus infection in children: the role of viral factors and an Immunocompromised state. J Pediatric Infect Dis Soc., 8(1):21–8.
Ogimi C, Waghmare AA, Kuypers JM, Xie H, Yeung CC, Leisenring WM, et al. (2017). Clinical significance of human coronavirus in Bronchoalveolar lavage samples from hematopoietic cell transplant recipients and patients with hematologic malignancies. Clin Infect Dis., ;64(11):1532–9.
Richardson S, H. J. (2020). Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID- 19 in the New York city area. JAMA, 323(20):2052–9.
Sarkar, S., Khanna, P., & Singh, A. K. . (2021). (2021). Impact of COVID‐19 in patients with concurrent co‐infections: a systematic review and meta‐analyses. . Journal of Medical Virology,, 93(4), 2385-2395.
Sigel K, Swartz T, Golden E, et al. (2020). Covid-19 and People with HIV Infection: Outcomes for Hospitalized Patients in New York City. Clin Infect Dis., ciaa880. doi:10.1093/cid/ciaa880.
Soriano V, Barreiro P. (2020). Impact of new coronavirus epidemics on HIV-infected patients. AIDS Rev., 22(1):57–8.
Ssentongo, P., Heilbrunn, E. S., Ssentongo, A. E., Advani, S., Chinchilli, V. M., Nunez, J. J., & Du, P. (2021). (2021). Epidemiology and outcomes of COVID-19 in HIV-infected individuals: a systematic review and meta-analysis. . Scientific reports, , 11(1), 1-12.
Stochino C, Villa S, Zucchi P, et al. (2020). . Clinical characteristics of COVID-19 and active tuberculosis co-infection in an Italian reference hospital. Eur Respir J, 56: 2001708. https:// doi.org/10.1183/ 13993003. 01708-2020].
Suwanwongse K, Shabarek N. (2020). Clinical features and outcome of HIV/SARS-CoV-2 co-infected patients in the Bronx, New York City. J Med Virol, doi: 10.1002/jmv.26077.
Tadolini M, Codecasa LR, García-García J-M, et al. . ((2020). Active tuberculosis, sequelae and COVID-19 co-infection: first cohort of 49 cases. . Eur Respir J , 56: 2001398. https://doi.org/10.1183/ 13993003. 01398-2020.
Tesoriero, J. M., Swain, C. A. E., Pierce, J. L., Zamboni, L., Wu, M., Holtgrave, D. R.,& Rosenberg, E. S et al . (2020). Elevated COVID-19 outcomes among persons living with diagnosed HIV infection in New York State: Results from a population-level match of HIV, COVID-19, and hospitalization databases. medRxiv., doi: 10.1001/jamanetworkopen.2020.37069.
Wallinga J, T. P. (2004). Different epidemic curves for severe acute respiratory syndrome reveal similar impacts of control measures. . Am J Epidemiol. , 160(6):509–16.
Published
2021-09-29
How to Cite
Atmojo, J., Arradini, D., Ernawati, E., Darmayanti, A., Kuntari, S., Hanifah, L., Handayani, R., & Widiyanto, A. (2021). Meta Analisis Risk Ratio dan Hazard Ratio Kematian ODHA yang Terinfeksi Covid-19. Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal, 11(4), 905-916. https://doi.org/https://doi.org/10.32583/pskm.v11i4.1673
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Articles
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