Upaya Peningkatkan CD4 pada Orang dengan HIV: Systematic Review
Keywords:
CD4, HIV, nursing, RCT
Abstract
HIV adalah virus yang menyerang sistem kekebalan dan selanjutnya melemahkan kemampuan tubuh untuk melawan infeksi. HIV tidak dapat disembuhkan dan fungsi kekebalanitingkatkan dengan aktivasi pemberian terapi antiretroviral. Prinsip perawatan pasien HIV adalah meningkatkan CD4/ imunitas. Tujuan penelitian untuk mengetahui berbagai upaya dalam meningkatkan CD4 pada orang dengan HIV. Systematic review dengan strategi pencarian dan sumber data menggunakan kata kunci: HIV; NURSING; CD4; RCT. Strategi pencarian mulai tahun 2016 sampai dengan 2020 dengan mengidentifikasi studi yang dipublikasikan dalam database elektronik JSTOR, Cambridge core, Nature, Science Direct, Emerald insight, Springerlink, Scopus, Ebsco, ProQuest, Clinical Key, Google Scholar. Terdapat empat belas hasil penelitian yaitu jalan cepat dan aerobik (n=4), konseling (n=3), pemberian suplemen zinc dan vitamin D (n=2), yoga (n= 2), mindfulness dan Cognitive Behavioral Therapy (CBT) (n=2) dan dukungan teman sebaya (n=1) yang dapat meningkatkan jumlah CD4. Asuhan keperawatan pada orang HIV dengan meningkatkan daya tahan tubuh dan terdapat empat belas hasil penelitian untuk meningkatkan jumlah CD4 selain tetap mengkonsumsi terapi ARV, yaitu jalan cepat dan aerobik, konseling, pemberian suplemen zinc dan vitamin D, yoga, mindfulness dan Cognitive Behavioral Therapy (CBT) dan dukungan teman sebaya.
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Chatha, Zeenat Fatima, Usman Rashid, Sharon Olsen, Fakhar ud Din, Amjad Khan, Komal Nawaz, Siew Hua Gan, and Gul Majid Khan. 2020. “Pharmacist-Led Counselling Intervention to Improve Antiretroviral Drug Adherence in Pakistan: A Randomized Controlled Trial.” BMC Infectious Diseases 20 (1): 1–10. https://doi.org/10.1186/s12879-020-05571-w.
Clavel, Frederick, Frederick D Clavel, Carolyn E Cutrona, Marcus Crede, Susan E Cross, Zlatan Krizan, and Daniel W Russell. 2017. “Couples Social Support Quality in the Context of Dyadic Emotional Experiences.” https://lib.dr.iastate.edu/etd/16115.
Creswell, J. David, Hector F. Myers, Steven W. Cole, and Michael R. Irwin. 2009. “Mindfulness Meditation Training Effects on CD4+ T Lymphocytes in HIV-1 Infected Adults: A Small Randomized Controlled Trial.” Brain, Behavior, and Immunity 23 (2): 184–88. https://doi.org/10.1016/j.bbi.2008.07.004.
Cuong, Do Duy, Anders Sönnerborg, Vu Van Tam, Ziad El-Khatib, Michele Santacatterina, Gaetano Marrone, Nguyen Thi Kim Chuc, et al. 2016. “Impact of Peer Support on Virologic Failure in Hiv-Infected Patients on Antiretroviral Therapy - a Cluster Randomized Controlled Trial in Vietnam.” BMC Infectious Diseases 16 (1): 1–14. https://doi.org/10.1186/s12879-016-2017-x.
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Dianatinasab, Mostafa, Mohammad Fararouei, Valiollah Padehban, Aria Dianatinasab, Yousef Alimohamadi, Shohreh Beheshti, Zeinab AminiLari, and Mahmood AminiLari. 2018. “The Effect of a 12-Week Combinational Exercise Program on CD4 Count and Mental Health among HIV Infected Women: A Randomized Control Trial.” Journal of Exercise Science and Fitness 16 (1): 21–25. https://doi.org/10.1016/j.jesf.2018.02.001.
Dwi Retnaningsih, MY Martini, Windyastuti. 2017. “SEXUALLY TRANSMITTED DISEASES PREVENTIVE BEHAVIOR AMONG FEMALE SEX WORKERS.” Jurnal Pendidikan Dan Praktik Keperawatan Indonesia 2 (2).
Fisher, Jeffrey D., William A. Fisher, K. Rivet Amico, and Jennifer J. Harman. 2006. “An Information-Motivation-Behavioral Skills Model of Adherence to Antiretroviral Therapy.” Health Psychology 25 (4): 462–73. https://doi.org/10.1037/0278-6133.25.4.462.
Ford, Nathan, Graeme Meintjes, Marco Vitoria, Greg Greene, and Tom Chiller. 2017. “The Evolving Role of CD4 Cell Counts in HIV Care.” Current Opinion in HIV and AIDS 12 (2): 123–28. https://doi.org/10.1097/COH.0000000000000348.
Gazzola, Lidia, Camilla Tincati, Giusi Maria Bellistrì, Antonella D.Arminio Monforte, and Giulia Marchetti. 2009. “The Absence of CD4+ T Cell Count Recovery despite Receipt of Virologically Suppressive Highly Active Antiretroviral Therapy: Clinical Risk, Immunological Gaps, and Therapeutic Options.” Clinical Infectious Diseases 48 (3): 328–37. https://doi.org/10.1086/595851.
Ghayomzadeh, Morteza, Maede Sadat Etesami, Conrad P. Earnest, Sajjad Rezaei, James Wilfred Navalta, Leila Taj, Seyed Ahmad SeyedAlinaghi, Minoo Mohraz, Reza Gharakhanlou, and Fabrício Azevedo Voltarelli. 2019. “Effect of a Short-Term Lifestyle Modification Program on Quality of Life, Anthropometric Characteristics and CD4+T Cell Count of HIV Infected Patients in Tehran/Iran: A Randomized Controlled Trial.” Explore 15 (4): 308–15. https://doi.org/10.1016/j.explore.2019.01.004.
Ghayomzadeh, Morteza, Seyedahmad Seyedalinaghi, Mahdieh M. Shamsi, Sajjad Rezaei, Conrad P. Earnest, Sima Akbarnejad, Leila Taj, et al. 2019. “Effect of 8 Weeks of Hospital-Based Resistance Training Program on TCD4+ Cell Count and Anthropometric Characteristic of Patients with HIV in Tehran, Iran: A Randomized Controlled Trial.” Journal of Strength and Conditioning Research 33 (4): 1146–55. https://doi.org/10.1519/JSC.0000000000002394.
Gnatienko, Natalia, Matthew S. Freiberg, Elena Blokhina, Tatiana Yaroslavtseva, Carly Bridden, Debbie M. Cheng, Christine E. Chaisson, et al. 2018. “Design of a Randomized Controlled Trial of Zinc Supplementation to Improve Markers of Mortality and HIV Disease Progression in HIV-Positive Drinkers in St. Petersburg, Russia.” HIV Clinical Trials 19 (3): 101–11. https://doi.org/10.1080/15284336.2018.1459344.
Gonzalez-Garcia, Marian, Maria Jose Ferrer, Xavier Borras, Jose A. Muñoz-Moreno, Cristina Miranda, Jordi Puig, Nuria Perez-Alvarez, et al. 2014. “Effectiveness of Mindfulness-Based Cognitive Therapy on the Quality of Life, Emotional Status, and CD4 Cell Count of Patients Aging with HIV Infection.” AIDS and Behavior 18 (4): 676–85. https://doi.org/10.1007/s10461-013-0612-z.
Han, Shuyu, Yan Hu, Hongzhou Lu, Lin Zhang, Zheng Zhu, Jianfeng Luo, Michael V. Relf, Marta I. Mulawa, Yaolin Pei, and Bei Wu. 2020. “Cognitive Behavioral Therapy for Persons Living with HIV in China: A Randomized Pilot Trial.” Journal of Affective Disorders 277 (February): 640–48. https://doi.org/10.1016/j.jad.2020.08.085.
Jam S, Imani AH, Foroughi M, SeyedAlinaghi S, Koochak HE, Mohraz M. 2010. “The Effects of Mindfulness-Based Stress Reduction (MBSR) Program in Iranian HIV/AIDS Patients: A Pilot Study.” Acta Med Iran 48 (2).
Julian Higgins, Sally Green. 2008. Cochrane Handbook for Systematic Reviews of Interventions. IEEE International Symposium on Information Theory - Proceedings. https://doi.org/10.1109/ISIT.2017.8006970.
Kiecolt-Glaser, Janice K., Lynanne McGuire, Theodore F. Robles, and Ronald Glaser. 2002. “Psychoneuroimmunology: Psychological Influences on Immune Function and Health.” Journal of Consulting and Clinical Psychology 70 (3): 537–47. https://doi.org/10.1037/0022-006X.70.3.537.
LaPerriere, A., N. Klimas, M. A. Fletcher, A. Perry, G. Ironson, F. Perna, and N. Schneiderman. 1997. “Change in CD4+ Cell Enumeration Following Aerobic Exercise Training in HIV-1 Disease: Possible Mechanisms and Practical Applications.” International Journal of Sports Medicine, Supplement 18 (SUPPL. 1). https://doi.org/10.1055/s-2007-972700.
McPherson-Baker, S., R. M. Malow, F. Penedo, Deborah L. Jones, N. Schneiderman, and N. G. Klimas. 2000. “Enhancing Adherence to Combination Antiretroviral Therapy in Non-Adherent HIV-Positive Men.” AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV 12 (4): 399–404. https://doi.org/10.1080/09540120050123792.
Menon, JA, and C Glazebrook. 2013. “Randomized Control Trial to Evaluate Yoga-Based Peer Support Group for Human Immunodeficiency Virus (HIV) Positive Zambian Adolescents.” Journal of AIDS and HIV Research 5 (1): 12–19. https://doi.org/10.5897/JAHR12.027.
O’Brien, Kelly K., Anne Marie Tynan, Stephanie A. Nixon, and Richard H. Glazier. 2016. Effectiveness of Aerobic Exercise for Adults Living with HIV: Systematic Review and Meta-Analysis Using the Cochrane Collaboration Protocol. BMC Infectious Diseases. Vol. 16. BMC Infectious Diseases. https://doi.org/10.1186/s12879-016-1478-2.
Ozemek, Cemal, Kristine M. Erlandson, and Catherine M. Jankowski. 2020. “Physical Activity and Exercise to Improve Cardiovascular Health for Adults Living with HIV.” Progress in Cardiovascular Diseases 63 (2): 178–83. https://doi.org/10.1016/j.pcad.2020.01.005.
Phillips, Kenneth D, Robin F Harris, and Lisa M Haddad. 2019. Virus / AIDS. Handbook of Sleep Disorders in Medical Conditions. Elsevier Inc. https://doi.org/10.1016/B978-0-12-813014-8.00013-5.
Pomatahu, Aisah R. n.d. “SENAM AEROBIK (Mosesahi) UNTUK KESEHATAN PARU.”
Ramírez-Marrero, Farah A., Barbara A. Smith, Nelson Meléndez-Brau, and Jorge L. Santana-Bagur. 2004. “Physical and Leisure Activity, Body Composition, and Life Satisfaction in HIV-Positive Hispanics in Puerto Rico.” Journal of the Association of Nurses in AIDS Care 15 (4): 68–77. https://doi.org/10.1177/1055329003261966.
Retnaningsih, Dwi. 2015. “Pengelolaan Universal Precaution Dalam Pencegahan Penyakit Hiv / Aids Di Rsud Tugurejo Semarang.” Intrnasional, 215–23.
Ridgway, Jessica P., Jessica Schmitt, Eleanor Friedman, Michelle Taylor, Samantha Devlin, Moira McNulty, and David Pitrak. 2020. “HIV Care Continuum and COVID-19 Outcomes Among People Living with HIV During the COVID-19 Pandemic, Chicago, IL.” AIDS and Behavior. https://doi.org/10.1007/s10461-020-02905-2.
Rosy Naoroibam, Kashinath G Metri, HR Nagendra. 2016. “Effect of Integrated Yoga (IY) on Psychological States and CD4 Counts of HIV-1 Infected Patients: A Randomized Controlled Pilot Study.” International Journal of Yoga 9 (1): 57–61. https://doi.org/10.4103/0973-6131.171723.
Scrimshaw, N. S., and J. P. SanGiovanni. 1997. “Synergism of Nutrition, Infection, and Immunity: An Overview.” American Journal of Clinical Nutrition 66 (2): 464–77. https://doi.org/10.1093/ajcn/66.2.464S.
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Published
2021-05-01
How to Cite
Retnaningsih, D., Handayani, F., & Sujianto, U. (2021). Upaya Peningkatkan CD4 pada Orang dengan HIV: Systematic Review. Jurnal Keperawatan, 13(2), 299-310. https://doi.org/https://doi.org/10.32583/keperawatan.v13i2.1276
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